Conference Program

Friday, April 11, 2025

15:00 – 21:00: Registration

Saturday, April 12, 2025

08:30: Opening Ceremony

Session 1 (Chair: Dr Richard Wintle)

09:30 – 10:20: Keynote – A/Prof Siddharth Srivastava: "The Genetic Landscape of Cerebral Palsy and Related Neurodevelopmental Disorders: Setting a Roadmap for the Next 10 Years"

10:20 – 10:40: Tea Break

Session 2 (Chair: Dr Richard Wintle)

10:40 – 11:20: Prof Darcy Fehlings: "'Genetic' and 'Environmental' Etiologic Risk in Cerebral Palsy: Current Knowledge and Potential Next Steps"

11:20 – 12:00: Prof Sarah McIntyre: "The Epidemiology of Cerebral Palsy and the Impact of Cerebral Palsy Registers"

12:00 – 12:20: Dr Teerada Ployptech: "Goal Directed Training – A Practical Approach for LMICs"

12:20 – 13:30: Lunch

Session 3 (Chair: Prof Michael Fahey)

13:30 – 14:05: Dr Clare van Eyk: "Who to Test and What Test to Do? Perspectives on Genomic Testing from the Australian Cerebral Palsy Biobank Cohort"

14:05 – 14:40: Prof Marije Meuwissen: "The Genetic Puzzle of Cerebral Palsy: Results of a Monocentric Study"

14:40 – 14:55: (Short Talk) Junying Yuan: "The Relationship Between MRI Patterns Based on MRICS and Clinical Characteristics in CP Children"

14:55 – 15:10: (Short Talk) Wenkai Yu: "In-depth Serum Proteomics Reveals Diagnostic Biomarkers and Molecular Pathways in Cerebral Palsy"

15:10 – 15:30: Tea Break

Session 4 (Chair: Prof Jozef Gecz)

15:30 – 16:00: Dr Heather Pierce: "Whole Genome Diagnosis in a UK Cohort of Children with Cerebral Palsy"

16:00 – 16:30: Dr Richard Wintle: "Comprehensive Whole Genome Annotation in Canadian Cerebral Palsy Cohorts"

16:30 – 17:00: Prof Hao Hu: "Integrated Stress Response as a Therapeutic Target for tRNA-Linked Neurodevelopmental Disorders"

17:00 – 17:15: (Short Talk) Yimeng Qiao et al: "PPP1R3F Variants Disrupt Energy Metabolism and Suggest a Novel Genetic Basis for Neurodevelopmental Disorders"

17:15 – 18:30: Panel Discussion – "What Constitutes Cerebral Palsy in the Era of Genomics?"  Moderator: Dr Richard Wintle

Panelists: Prof Fehlings, Prof Srivastava, Prof McIntyre, Dr Pierce, Prof Meuwissen, Prof Hu   

18:30 – 20:30: Dinner

Sunday, April 13, 2025

Session 5 (Chair: Dr Clare van Eyk)

08:30 – 09:00: Ms Yana Wilson: "Disability Outcomes in Siblings of Children with CP"

09:00 – 09:30: Prof Xiaoyang Wang: "Can Spatial Transcriptomics Uncover the Molecular Basis of Cerebral Palsy?"

10:00 – 10:15: (Short Talk) Dr Hui Gao et al: "Metabolic and Synaptic Defects in HPDL-Deficient Mice Link Mitochondrial Dysfunction to Neurodevelopmental Disorders"

10:15 – 10:40: Tea Break

Session 6 (Chair: Prof Hao Hu)

10:40 – 11:10: Prof Quinghe Xing: "Dominant Variants of KINDINS220 in Cerebral Palsy"

11:10 – 11:40: Prof Michael Fahey: "Stem Cells and CP"

11:40 – 11:55: (Short Talk) Na Li et al: "EMC10 Deficiency Linked to Neurovascular Dysfunction and White Matter Degeneration in Zebrafish and Mouse Models"

11:55 – 12:10: (Short Talk) Wendong Li et al: "α1-antitrypsin Modulates the p38 MAPK Pathway to Improve the Neuroinflammatory Response After Immature WMI in Mice"

12:10 – 13:10: Lunch

Session 7 (Chair: Dr Heather Pierce)

13:10 – 13:40: Prof Ugur Ozbek: "New Generation Sequencing Approach to Solve the Turkish CP Patients Cohort"

13:40 – 13:55: (Short Talk) Claudio D'Incal: "ADNP and Helsmoortel-Van der Aa Syndrome"

13:55 – 14:10: (Short Talk) Song Juan and Zhang Xinling: "Risk Factors and Prediction Model for Cerebral Palsy in Term Infants with Subcortical Leukomalacia"

14:10 – 14:25: (Short Talk) Aiyun Yuan et al: "Survival Status and Challenges of Children and Adolescents with Spinal Muscular Atrophy in China"

14:25 – 15:25: Poster Session

15:25 – 15:40: Tea Break

Session 8 (Chair: Prof Sarah McIntyre)

15:40 – 16:10: Prof Jozef Gecz: "Molecular Mechanisms of CP"

16:10 – 16:40: Prof Changlian Zhu: "Bridging Clinical Practice and Genetic Research in Cerebral Palsy: Insights from Chinese Studies"

16:40 – 16:55: (Short Talk) Sun Haonan et al: "Cognitive Rehabilitation Program Based on Mindfulness Training for Children with Cerebral Palsy"

17:05 – 17:20: (Short Talk) Suya Yuan et al: "Effect of Robot-Assisted Gait Training Combined with Task-Oriented Training on Walking Ability in Children with Dyskinetic Cerebral Palsy"

17:20 – 17:35: (Short Talk) Liuyang Zhang et al: "Integrating Whole-Genome and RNA Sequencing to Enhance Diagnostic Precision in Cerebral Palsy"

17:35 – 18:00: Closing Remarks & Conference Awards

Prof Changlian Zhu (Local Organising Committee)

Prof Jozef Gecz (Program Committee)

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